- Adopted his sister's children after his brother-in-law died in November 2014. His sister had died in 2007.
- Luke and his wife, Caroline Bryan, were college sweethearts.
- Luke and his wife, Caroline Bryan, welcomed a son, Thomas Boyer Bryan, on March 18, 2008 in Nashville.
- Luke and his wife, Caroline Bryan, welcomed their 2nd child, a son named Tatum "Tate" Christopher, on August 11, 2010 at 9:48 A.M.
- Country music singer.
- His infant niece, Sadie Brett (born in the summer 2016), died on February 21, 2017, after battling undisclosed cardiac issues, among several other health problems. Sadie was the daughter of Bryan's wife Caroline's brother, Bo Boyer, and his wife, Ellen Boyer.
- Friend of Willie Robertson.
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