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- CreatorDavid LittMichael J. WeithornStarsKevin JamesLeah ReminiJerry StillerDeliveryman Doug Heffernan has a good life: He has a pretty wife (Carrie), a big television, and friends with which to watch it. Then Carrie's goofy, annoying father Arthur moves in with them.
- CreatorLarry DavidJerry SeinfeldStarsJerry SeinfeldJulia Louis-DreyfusMichael RichardsThe continuing misadventures of neurotic New York City stand-up comedian Jerry Seinfeld and his equally neurotic New York City friends.
- CreatorDavid AngellPeter CaseyDavid LeeStarsKelsey GrammerJane LeevesDavid Hyde PierceDr. Frasier Crane moves back to his hometown of Seattle, where he lives with his father and works as a radio psychiatrist.
- CreatorPaul T. ScheuringStarsDominic PurcellWentworth MillerAmaury NolascoA structural engineer installs himself in a prison he helped design, in order to save his falsely accused brother from a death sentence by breaking themselves out from the inside.
- CreatorJ.J. AbramsJeffrey LieberDamon LindelofStarsJorge GarciaJosh HollowayYunjin KimThe survivors of a plane crash are forced to work together in order to survive on a seemingly deserted tropical island.
- CreatorLee AronsohnChuck LorreStarsJon CryerAshton KutcherAngus T. JonesA hedonistic jingle writer's free-wheeling life comes to an abrupt halt when his brother and 10-year-old nephew move into his beach-front house.
- CreatorGregory Thomas GarciaStarsJason LeeEthan SupleeJaime PresslyA ne'er do well wins $100,000 in the lottery and decides to right all the wrongs from his past with his newfound realization!
- CreatorBill LawrenceStarsZach BraffDonald FaisonSarah ChalkeIn the unreal world of Sacred Heart Hospital, intern John "J.D." Dorian learns the ways of medicine, friendship and life.
- CreatorTom KapinosStarsDavid DuchovnyNatascha McElhoneEvan HandlerA writer tries to juggle his career, his relationship with his daughter and his ex-girlfriend, as well as his appetite for beautiful women.
- CreatorRon LeavittMichael G. MoyeStarsEd O'NeillChristina ApplegateKatey SagalAl is the quintessential working class dad. Peggy, his wife, always wants more from him. With their children, they go through the highs and lows of ordinary life.
- CreatorSeth MacFarlaneDavid ZuckermanStarsAlex BorsteinSeth MacFarlaneSeth GreenIn a wacky Rhode Island town, a dysfunctional family strives to cope with everyday life as they are thrown from one crazy scenario to another.
- CreatorMike BarkerSeth MacFarlaneMatt WeitzmanStarsSeth MacFarlaneWendy SchaalScott GrimesThe escapades of Stan Smith, a conservative C.I.A. Agent dealing with family life, and keeping America safe.
- CreatorJames L. BrooksMatt GroeningSam SimonStarsDan CastellanetaNancy CartwrightHarry ShearerThe satiric half-hour adventures of a working-class family in the misfit city of Springfield.
- CreatorRod SerlingStarsForest WhitakerJune B. WildeChris ShieldsThis second revival of The Twilight Zone (1959) presents tales of suspense, fantasy, science fiction and horror.
- CreatorMichael CrichtonStarsAnthony EdwardsGeorge ClooneyJulianna MarguliesThe doctors who work in the ER at the County General Hospital in Chicago grapple with ups and downs in their personal and professional lives while trying to give apt medical care to their patients.
- CreatorChris CarterStarsDavid DuchovnyGillian AndersonMitch PileggiTwo F.B.I. Agents, Fox Mulder the believer and Dana Scully the skeptic, investigate the strange and unexplained, while hidden forces work to impede their efforts.
- CreatorJames BurrowsGlen CharlesLes CharlesStarsTed DansonRhea PerlmanJohn RatzenbergerThe regulars of the Boston bar "Cheers" share their experiences and lives with each other while drinking or working at the bar where everybody knows your name.
- CreatorLarry GelbartStarsAlan AldaWayne RogersLoretta SwitThe staff of an Army hospital in the Korean War find that laughter is the best way to deal with their situation.
- CreatorDale McRavenStarsBronson PinchotMark Linn-BakerMelanie WilsonA high-strung and cynical man's life is never the same when his naive but good-natured cousin comes to America to live with him.
- CreatorGary David GoldbergBill LawrenceStarsMichael J. FoxCharlie SheenHeather LocklearMike Flaherty, the Deputy Mayor of New York City, and his team of half-wits must constantly save the Mayor from embarrassment and the media. Mike is later succeeded by Charlie Crawford.
- CreatorDarren StarStarsHeather LocklearAndrew ShueCourtney Thorne-SmithClassic serial drama around a group of friends living in Melrose Place, California.
- CreatorShana Goldberg-MeehanScott SilveriStarsMatt LeBlancPaulo CostanzoDrea de MatteoIn this spin-off of Friends (1994), Joey Tribbiani moves to Los Angeles to pursue his acting career.
- CreatorDavid CraneMarta KauffmanStarsJennifer AnistonCourteney CoxLisa KudrowFollows the personal and professional lives of six twenty to thirty year-old friends living in the Manhattan borough of New York City.
- CreatorAli LeRoiChris RockStarsTerry CrewsTichina ArnoldTequan RichmondA young African-American teen attempts to survive with his dysfunctional family and his all-white school in the 1980s.
- CreatorPhil RosenthalStarsRay RomanoPatricia HeatonBrad GarrettThe comical everyday life of sports columnist Ray Barone and his dysfunctional family.