In 1926, magizoologist Newt Scamander arrives in New York during his worldwide tour to research and rescue magical creatures as something mysterious leaves trails of destruction in the city, threatening to expose the wizarding world.
Following the assassination of President John F. Kennedy, First Lady Jacqueline Kennedy fights through grief and trauma to regain her faith, console her children, and define her husband's historic legacy.
In the 17th century, two Portuguese Jesuit priests travel to Japan in an attempt to locate their mentor, who is rumored to have committed apostasy, and to propagate Catholicism.