Searching for a cure to Alzheimer's disease, a group of scientists on an isolated research facility become the prey, as a trio of intelligent sharks fight back.
When a killer shark unleashes chaos on a beach community off Cape Cod, it's up to a local sheriff, a marine biologist, and an old seafarer to hunt the beast down.
When a son of a gangster shark boss is accidentally killed while on the hunt, his would-be prey and his vegetarian brother decide to use the incident to their own advantage.
With a plan to exact revenge on a legendary shark that killed his partner, oceanographer Steve Zissou (Bill Murray) rallies a crew that includes his estranged wife, a journalist, and a man who may or may not be his son.