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- DirectorDeran SarafianStarsHugh LaurieLisa EdelsteinOmar EppsHouse must diagnose a man who became sick and experienced difficulty breathing during sex-play but all tests keep returning normal. Wilson experiences close-up what living with House is like. Clinic case: Herpes
- DirectorParis BarclayStarsHugh LaurieLisa EdelsteinOmar EppsHouse's ex Stacy Warner asks him to treat her husband. House takes over a diagnostics class for a day and presents the class with three case studies of leg pain. As House tells his story and the class gradually fills up with listeners, the class learns a lot about how to be better doctors, and Chase, Foreman and Cameron learn some important details of House's past.
- DirectorDaniel AttiasStarsHugh LaurieLisa EdelsteinOmar EppsA patient with 40% body burns and inexplicable cardiac and neurological signs is treated by the team, while House pursues disproving an old enemy's medical study.
- DirectorFélix Enríquez AlcaláStarsHugh LaurieLisa EdelsteinOmar Epps6 months after a teenage girl crushes her chest in a car accident and receives a heart transplant she goes into anaphylactic shock in her clean bedroom after her boyfriend almost kisses her and discovers something on her arm.
- DirectorFred GerberStarsHugh LaurieLisa EdelsteinOmar EppsOn a class field trip, a teacher discovers that her six-year-old student, Ian, is bleeding profusely. Dr. House thinks Ian has the same unknown disease that killed an elderly patient of his years ago.
- DirectorDeran SarafianStarsHugh LaurieLisa EdelsteinOmar EppsHouse treats a rock musician, and some of the candidates have to get past their personal biases, Wilson misdiagnoses a patient, and the winners are named.
- DirectorDavid StraitonStarsHugh LaurieLisa EdelsteinOmar EppsWhen a researcher at a South Pole base becomes ill, House must diagnose the case at a distance. Meanwhile, House tries to find out who Wilson is dating, and his new staff tries to get him cable.
- DirectorDavid PlattStarsHugh LaurieLisa EdelsteinOmar EppsHouse tries every delaying tactic available when Wilson forces him to attend his father's funeral. Meanwhile, the team tries to find the cause of a young woman's abdominal pain and hemorrhage that occurred in China.
- DirectorGreg YaitanesStarsHugh LaurieLisa EdelsteinOmar EppsHouse takes time to dabble in Cameron and Chase's love life while he treats an agoraphobic patient she's brought to the team.
- DirectorDaniel AttiasStarsHugh LaurieLisa EdelsteinOmar EppsHouse is injured in a motorcycle accident. While recovering, he finds an accident victim suffering from a brain injury. House tries to prove the brain damage caused the accident, not vice versa, so he can treat the patient.
- DirectorKatie JacobsStarsHugh LaurieRobert Sean LeonardFranka PotenteHouse fights his doctors, the staff and his fellow patients when he's forced to stay in the psychiatric hospital under threat of permanently losing his medical license.
- DirectorGreg YaitanesStarsHugh LaurieLisa EdelsteinOmar EppsVince hallucinates during testing of a video game he's developing. House quits his old job after mental hospital. He joins Wilson in cooking class. Foreman takes over on trial.
- DirectorDavid StraitonStarsHugh LaurieLisa EdelsteinOmar EppsForeman hires Chase and Cameron as his new team. An African tyrant becomes Foreman and co.'s patient. They're not happy. House is back as consultant. House meets Wilson's downstairs neighbor.
- DirectorDavid SemelStarsHugh LaurieLisa EdelsteinOmar EppsChaos ensues after Chase's negligence leads to the death of a female patient. Now, after an inquiry from the hospital board, and a subpoena from the patient's brother, it's up to Stacey to protect Chase's career, as well as House's.
- DirectorLesli Linka GlatterStarsHugh LaurieLisa EdelsteinOmar EppsWhen an old friend and former patient of Wilson's experiences paralysis in his right arm, Wilson puts himself on the case. House wagers Wilson that the patient's symptoms result from new cancer cells. Wilson accepts even though he is reluctant to believe the cancer has returned. With the help of the team, Wilson works to find a more optimistic diagnosis, but when things take a turn for the worse, and Wilson must address his inability to separate patient from friend. Meanwhile, Cuddy seeks advice in her search for real estate.
- DirectorNick GomezStarsHugh LaurieLisa EdelsteinOmar EppsWhen drug dealer Mickey mysteriously collapses while negotiating a sale, his partner-in-crime, Eddie, accompanies him to Princeton Plainsboro for treatment. But with a major deal pending, Mickey is not forthcoming with the necessary personal information the team needs to treat him. As Mickey's condition worsens, the team resorts to old-fashioned detective work to solve the case. Meanwhile, House and Wilson compete for the affection of a new neighbor, and Chase, Thirteen and Taub attempt to play a practical joke on Foreman.
- DirectorAndrew BernsteinStarsHugh LaurieLisa EdelsteinOmar EppsThis is a hectic day in Cuddy's life from 5AM to 9PM. Giving an insurance company an ultimatum could bankrupt the hospital. She fires an employee for theft. Her child's sick. A patient won't pay for a reattached thumb.
- DirectorHugh LaurieStarsHugh LaurieLisa EdelsteinOmar EppsWhen a newborn disappears from the nursery, Princeton Plainsboro goes on lockdown, preventing anyone from entering, leaving or moving within the hospital. While House and his team members are trapped in various parts of the building, new insights about the team's personal histories, relationships and regrets surface.
- DirectorGreg YaitanesStarsHugh LaurieLisa EdelsteinOmar EppsHouse and Cuddy are exploring the ramifications of those feelings and attempting to make a real relationship work. Meanwhile, due to a colleague's illness, Princeton Plainsboro is left without a neurosurgeon on site, threatening the hospital's accreditation as a Level 1 Trauma Center. As the team attempts treatment to get their sick colleague back to work, they discover there is more to the illness than they originally suspected and turn to House for direction. Instead, House remains elusive, leaving the team on its own.
- DirectorGreg YaitanesStarsHugh LaurieLisa EdelsteinOmar EppsA newborn baby has problems breathing. House and team run diagnosis. House babysits Cuddy's daughter. Did she eat a dime? Foreman finds a new female doctor for the team. House fires her and Taub has to find a new one.
- DirectorDavid StraitonStarsHugh LaurieLisa EdelsteinOmar EppsA disciplinary training camp drill instructor collapses with back pain. One of the 24 boys joins him in hospital. Someone has access to Chase's social media account and credit card. Cuddy wants Rachel in a good preschool.
- DirectorMatt ShakmanStarsHugh LaurieLisa EdelsteinOmar EppsThe team treats a patient with a secret home life. House enlists help to participate in a spud gun competition.
- DirectorGreg YaitanesStarsHugh LaurieRobert Sean LeonardOmar EppsHouse gets parole at his hearing, but he still has to survive 5 more days in a prison filled with violent criminals. One of them wants 20 Vicodin "or else". He helps the prison doctor diagnose a patient.
- DirectorKate WoodsStarsHugh LaurieOmar EppsRobert Sean LeonardThere's money now to hire Chase, Taub and Adams. A "model citizen" gets a seizure while cheating on his wife in a motel. He's House's new team's first patient. Is Taub dad to any of "his" two babies?
- DirectorGreg YaitanesStarsHugh LaurieOmar EppsRobert Sean LeonardWhen a violent incident involving a patient has serious consequences for one staff member, House and the team are placed under review by Dr. Walter Cofield, Foreman's former mentor and current Chief of Neurology. As House and each member of his team recount the details of the dramatic and life-threatening incident, Cofield must weigh the team's unconventional brand of collaboration against their ability to save lives.
- DirectorMatt ShakmanStarsHugh LaurieOmar EppsRobert Sean LeonardChase is back. His first patient is a cute nun about to make her final vow. While still blaming House, he needs his help with his patient. House and Taub try to one-up each other with pranks.
- DirectorHugh LaurieStarsHugh LaurieOmar EppsRobert Sean Leonard6 y.o. Emily gets a nose bleed and faints. Her dad gets her to the hospital, her mom's a doctor. Wilson has cancer, House is there for him.
- DirectorBryan SingerStarsHugh LaurieLisa EdelsteinOmar EppsA college boy whose low blood pressure does not respond with IV fluids piques House's curiosity. Clinic Cases: A woman who had a cold last week, man with a sore throat, woman whose leg hurts after running 6 miles, a boy and his MP3 Player.
- DirectorMatthew FifeStarsHugh LaurieRobert Sean LeonardOmar EppsA one-hour retrospective special that will look back at this groundbreaking, seminal series and feature interviews with the series' stars and producers, special original content and other surprises.