As Harvard student Mark Zuckerberg creates the social networking site that would become known as Facebook, he is sued by the twins who claimed he stole their idea and by the co-founder who was later squeezed out of the business.
After Peter Parker is bitten by a genetically altered spider, he gains newfound, spider-like powers and ventures out to save the city from the machinations of a mysterious reptilian foe.
With Spider-Man's identity now revealed, Peter asks Doctor Strange for help. When a spell goes wrong, dangerous foes from other worlds start to appear, forcing Peter to discover what it truly means to be Spider-Man.