Was in a relationship with Matthew Perry from 2006-2012.
She graduated from the prestigious Hamilton Academy of Music in Los
Angeles, California, Class of 2000. Her classmates included actor
Emile Hirsch.
Her mother died of illness when she was 13 years old.
Grew up in a Reform Jewish family. Her ancestors were from Latvia, Austria, Lithuania, and Russia.
Godmother of Busy Philipps's daughter Birdie Silverstein.
Has a cat named Lisa Turtle.
Married her boyfriend of 2 years Tom Riley in Italy over Labor Day weekend following a 16-month-long engagement. (September 2017)
In 2003 she named her (male) cat Colbert, after Stephen Colbert, who at that time was a correspondent on The Daily Show (1996). As of May 2016, that cat was still alive.