- She shared a house with Alan Rickman in London in the early '80s.
- She was awarded an honorary OBE (Officer of the Order of the British Empire) in the 2015 Queen's Birthday Honours List for her services to mental health.
- Despite being in England since the 1970s, she is still an American citizen with an American passport.
- Has one son, Max (b.1988) and two daughters, Madeline (b. 1990) and Marina (b. 1993).
- In 2009 Ruby Wax became the patron of the UK charity Depression Alliance, and works to raise awareness about mental health. (Interview in Spring 2009 edition of DA's magazine "A Single Step").
- Is close friends with British Comediennes: Dawn French & Jennifer Saunders who all starred in Girls on Top (1985), along side rising star Tracey Ullman and the legendary Joan Greenwood. Wax has appeared on the highly successful BBC shows: French & Saunders (1987) once, The Comic Strip Presents (1992) featuring her buddies French & Saunders once, and Absolutely Fabulous (1992) which stars Saunders and is produced by French & Saunders Productions, many times. She has served as a script writer on Ab Fab as well and helped write Girls on Top with French & Saunders, with Ullman throwing in on two episodes.
- In the early 80s 'making-of' documentary of Supergirl (1984), Helen Slater (Kara/Supergirl) screen tests with one Ruby Wax.
- Was "attacked" by O.J. Simpson during his 1998 appearance on The Ruby Wax Show (1997). At the end of the episode, O.J. Simpson surprised Wax by "stabbing" her repeatedly with a banana while mimicking the theme music from Psycho (1960).
- She was awarded an honorary OBE (Officer of the Order of the British Empire) on February 17, 2016 at the Priory in Roehampton, Southwest London, England.
- Was a contestant on Ant and Dec's Gameshow Marathon, a part of ITV's 50th birthday celebrations.
- Is close friends with Roseanne Barr.
- Attended the wedding of Joan Collins and Percy Gibson.
- Mother of actress, Marina Bye.
- Daughter and only child of Berta Goldmann Wachs and Edmund Wachs.
- Playing The Grand High Witch in the musical The Witches in the West End. (March 2005)
- Now doing radio and TV shows for the BBC in London; has no long-term plans to return to the States. (May 2003)
- She was awarded an honorary doctorate from the University of East London on November 3, 2016 in East London, England.
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