- She was the winner of Miss India Universe 1997 and was a semi-finalist in the Miss Universe pageant.
- Cousin of Saif Ali Khan. Nafisa's mother Usha Joesph is Sharmila's first cousin.
- She was engaged to actor Rahul Bose.
- She also acted in a television series C.A.T.S., an Indian version of Charlie's Angels for Sony Entertainment Television.
- She was groomed as a model by Prasad Bidapa.
- Joseph started modelling at age 12 when her neighbour got her an opportunity to model for a Wearhouse ad.
- Joseph hanged herself in her flat in Versova on 29 July 2004. She was to marry businessman Gautam Khanduja in a few weeks' time. According to her parents, Joseph took the step because her marriage was called off. This was due to Joseph having discovered that Khanduja was still married, although having told her he had been divorced for two years. When confronted, Khanduja refused to answer questions about his marital life or produce divorce papers that he had previously claimed he had filed. Instead, press reports at the time mention that he then threatened her with blackmail, probably after she threatened to confront his wife.
- Joseph was the youngest participant at the Miss India pageant in 1997, which she won.
- She edited a magazine called Gurlz.
- She was an Indian model and MTV video jockey.
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