- Daughter of Rosie O'Donnell.
- (July 1, 2016) Married her boyfriend of 8 months Nicholas Alliegro.
- Has four siblings, two brothers and two sisters: Parker Jaren O'Donnell (b. May 25, 1995), Blake Christopher O'Donnell (b. December 5, 1999), Vivienne Rose O'Donnell (b. November 29, 2002) and Dakota O'Donnell Rounds (b. January 5, 2013).
- Chelsea announced in September 2017 that she was expecting a baby with Nicholas Alliegro due in early May 2018, but she never provided further updates. It is unclear what happened with that pregnancy.
- (April 19, 2018) Filed for divorce from her husband of 21 months Nicholas Alliegro.
- Has a daughter, Skylar Rose Bourassa (b. December 2018), with her boyfriend Jacob Bourassa.
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