This gem just isn't given enough play. Actually, given the power of the forces it takes to task, it is a small miracle it even got made. In tackling the project, Mank riddled the medical profession, with a not too subtle sidetrip to take on McCarthyism.
Cary Grant is more smooth and relaxed than usual, and actually seems to be enjoying the role. Jeanne Crain tackles a difficult (and not too well written, alas) part, and Walter Slezak does a nice turn as a collegue and crony of Grant's. Hume Cronyn is despicable as the jealous and zealous pracitioner, prosecutor and persecutor.
This film didn't do well initially, but is now developing a cult following. It is one of those rare movies that gets better with each viewing.