The "Eyes" segment was Steven Spielberg's professional debut as a director. This was quite an auspicious beginning, considering that he was to direct screen legend Joan Crawford, winner of an Academy Award who had been acting in films since 1925.
In the first segment, in the scene in which Roddy McDowall shouts, "What in God's name is happening?" the sound track was faulty. During editing, McDowall was no longer available, so director John Badham himself looped the line.
Actor Richard Kiley was forty-seven years old when he acted in "Night Gallery". That would make him much younger than the character he played - Josef Strobe was a major general in the SS twenty-four years earlier, so he would have to be in his sixties at least.
This is second of two Joan Crawford vehicles in which she plays a woman who undergoes surgery to regain her sight. In This Woman Is Dangerous (1952), she played a similarly sight-impaired character who has a risky eye operation.