In a 2018 interview, Linnea Quigley talked about playing pranks on set during filming: "I like to play pranks depending on the people or set. Well, we were doing Creepozoids, and my love interest (Ken Abraham) was getting up at five in the morning to work out and watching what he ate. We did this shower scene, and they had rigged a water jug above us. We were both totally naked on boxes making out, trying not to fall off, and they were blowing smoke, and we got it done. He had been so nervous. Well, two days later, he is eating a lot and no gym, so I said to him 'Damn, I can't believe we have to reshoot the shower scene again.' He looked horrified. A bit later, I peek around the corner to see him doing push-ups and all to get into shape since he had slacked off."
A sequel was planned but never came to fruition.
Linnea Quigley said in couple Fangoria interviews how there was supposed to be more sexual scenes in the film involving her and the monster, which would result in her character being impregnated by it.
Shot in 15 days.
Linne Quigley's feet were so small they had to buy child's size boots for her.