SPOILER: Max Applewhite (Stephen Tobolowsky) is shot off the top of the radio tower by an airplane in a fashion similar to how King Kong was shot off the top of the Empire State Building by an airplane. (Also, the planes in both films look identical.)
Both films are set in show business settings and both are slapstick cartoonish in nature. Both of the main characters are named Roger and both are bumbling klutzes who are framed for murders they didn't commit. They both have seemingly marital problems that involves infieldility. Both voluptous redhead wives, (Jessica/Penny. Both movies have big stars in cameo roles like Bugs Bunny/George Burns. Both have villains that have big ambitions (a freeway/Television). Also both have Chistopher Lloyd playing cartoonish characters.