This was the only animated movie DeForest Kelley did voice work for, as well as his final performance. In BTS footage, he referenced his character of Dr. McCoy from Star Trek by saying "I'm a doctor, not an animated appliance!"
Deanna Oliver, Timothy Stack, & Thurl Ravenscroft were the only voice actors to star in all three of the Brave Little Toaster movies.
In the book this sequel was based on, only Fanny, Microwave, Hearing Aid, Lab Calculator, Toaster, Radio, and Blanky (after sneaking on the laundry basket) went to Mars; while Lampy and Kirby stayed behind.
In the German dub, Toaster is voiced by a woman and Lampy by a man. In the previous film it was the opposite (since "Toaster" is a masculine word and "Lamp" a feminine word in that language)