Lupino Lane is suffering an attack of the nerves, so nerve specialist Wallace Lupino sends him to his private hospital.... which is no help.
Usually Lane's comedies operated off their settings, but here there's a good deal of thematic cohesion with symbols of restraint, of being tangled up in various things, like watch chains, stethoscope tubes, skeletons and surgical bandages. I don't imagine it started out that way when he was setting up this comedy short, but as he and Wallace worked out the gags, they noticed that association and looked for similar gags.