The structure and concept of this script (which for the most part follows Xander on what--in a more usual episode--would be a subplot, while the series' more conventionally main characters are relegated to the background) is an homage to Tom Stoppard's 1966 existentialist play Rosencrantz and Guildenstern Are Dead, which follows the action of two relatively minor characters from William Shakespeare's "Hamlet" while using the actual main plot and characters from 'Hamlet' as occasional background and diversion.
Nicholas Brendon cried when he read the script because he was "so delighted with it, and its meaning for his character."
In an August 2013 Entertainment Weekly interview, Joss Whedon said that his then-upcoming ABC/Marvel comics television show Agents of S.H.I.E.L.D. (2013) would be "basically a TV series of "The Zeppo", which was a very deliberate deconstruction in order to star the person who mattered the least. The people who are ignored are the people I've been writing as my heroes from day one."
The shot of the cafeteria food - sauerkraut, hot dogs, and spaghetti - is the same clip used in I Only Have Eyes for You (1998). At that time, the food turns into snakes.
Jack's comment was cut for length: "That's it. No way am I bringing him back after I kill him."