In one of the last shots Sam straightens a photograph of Geronimo on the back wall. This is an homage to the late Nicholas Colasanto, who played "Coach" Ernie Pantusso from 1982-1985. The picture held special meaning to Colasanto who hung it in his dressing room. When he died in 1985, the picture was relocated to the set in his memory.
Ted Danson, Rhea Perlman and George Wendt are the only actors to appear in all 273 episodes of the series.
This is the only time that Diane and Rebecca appeared together onscreen.
While the gang was smoking cigars and discussing the meaning of life, Frasier Crane's voice started trembling, as he sounded somewhat emotionally distraught while trying to finish his sentence. Kelsey Grammer's struggling with his words was not scripted, as he was genuinely sad while filming the very last scene with his co-stars of nine years. George Wendt ad libbed the comment regarding Cliff's perception of shoes, in an effort to ease Kelsey Grammer's heart a little.
The person who walks up and knocks on the door in the last scene is Bob Broder, agent for the show's creators Glen Charles and Les Charles and James Burrows.