Pratt refers to an obscure diagnosis as a "zebra". This is a reference to a popular medical school adage about considering common diagnoses before considering obscure ones: "When you hear hoof-beats behind you, think horses, not zebras." (The saying originated with Dr. Theodore Woodward at the University of Maryland, who originally said simply, "Don't look for zebras on Greene Street," referring to the street in Baltimore where the University of Maryland Medical Center is.)
Full breast nudity is shown when the little girl and her grandmother come in. The doctors open the grandma's shirt to begin working on her and the little girl screams that her grandma doesn't like to be naked. They freeze on the doctors hovering over her exposed breasts. Very uncommon for network television.
Pratt deals with a patient called Mathers. Mathers is the surname of Eminem (Marshall Mathers). Mekhi Phifer (Pratt) played opposite Eminem in 8 Mile.