$4.3 billion dollars may seem a ludicrous amount for Fry's bank account, but it is correct. Starting with 93 cents, compound interest of 2.25% over 1000 years comes to exactly $4,283,508,449.71.
This episode marks the first appearance of Scruffy the janitor, although he is not identified by name, and is not yet working at Planet Express. He appears in a spa, massaging Bender with an orbital sander. His mustache is brown, not yet its more familiar grey.
This is the first episode to be rated TV-14 (the series main rating) for language. Understandable, as it's also the first appearance of Mom, the series main antagonist and possibly most vulgar character.
Originally Richard Nixon was suppose to help Mom recreate the 20th Century pizzeria, but the idea was scrapped. A Nixon poster appears on the wall anyway.