As tuberculosis is a highly infectious bacterial respiratory infection, a person with TB would isolate in the hospital, and staff would wear protective equipment at all times.
The pharmaceutical company that sponsors Sebastian is called "Stoia," like Chris Stoia, first assistant director on the show.
House refers to the Nobel prize as "blood money" on the grounds that "Nobel invented dynamite." Alfred Nobel founded the Nobel prize because of his guilt over the invention of dynamite, which he created as a construction tool and watched get used as a weapon, with the significant amount of money he got from the invention.
The title is based upon the often-used quote from William Shakespeare's play Hamlet, "To be or not to be."