Gandhi offers a rebuttal to a joke Hillary Clinton made at his expense. The main comedy segment is Live via Satellite, where Conan interviews "George W. Bush", "Al Sharpton", and "Steve Irwin". Benicio Del Toro is interviewed about his new film "21 Grams". Richard Lewis is interviewed about his role in the HBO series "Curb Your Enthusiasm". Maroon 5 performs.—Ian Lueck