While Toby is in the hospital room with his babies, the television is playing what is supposed to be home movie footage of Zoey as a child with her father. Even though the younger Jed Bartlet in the home movie is only seen very briefly, he is played by one of Martin Sheen's real-life sons, actor and director Emilio Estevez. This is the second time in their careers that Estevez has played a younger version of the same character that Martin Sheen was playing; the first time was in Nightbreaker (1989).
In the DVD commentary it is mentioned that the show had to deal with 12 - 16 real babies and their mothers for the scene in "25" where Toby has a private conversation with his newborn twins.
Director Christopher Misiano won the Emmy Award for outstanding directing in a Drama Series for this episode, the West Wing's last win in this category during it's run.
Martin Sheen, John Spencer and Stockard Channing were all nominated for an Emmy Award for their performances on this episode. Aaron Sorkin was also nominated for writing, though none of them eventually won.