When House pulls up to his home on his motorcycle, the house address reads "221". In Season 2, Episode 3, the house number was shown as "221B", a reference to Sherlock Holmes, who lived at 221B Baker Street, and shared several character traits with Dr. Gregory House.
House claims that Australian ants are harmless, and yet the Australian bull-ant, Myrmecia, has extremely potent venom, and the formic acid contained in its venom will readily cause anaphylaxis in people sensitive to bee sting or similar. They are also highly aggressive when disturbed and will swarm to protect their nest.
House, while making the case that the patient's wife is poisoning him, says that she hasn't left the hospital since the two of them arrived. Actually, she has left the hospital at least once; she was there when Foreman was in her house.