Heather North replaces the role of Stefanianna Christopherson, continuing to voice the character until 1997.
Dr. Jekyll looks uncannily similar to Professor Wayne from Scooby's Night with a Frozen Fright (1970). They are both voiced by John Stephenson.
Features the title characters from Robert Louis Stevenson's famous 1886 novel, "The Strange Case of Dr. Jekyll and Mr. Hyde."
The theme song has been re-recorded and many of the opening title sequences are updated.
When Stephaniana Christopherson left the show to get married, Heather North's roommate suggested that she should audition for the role of Daphne. Her roommate was none other than "Velma's" Nicole Jaffe. Heather won the role.