100th episode of the series.
This is the first episode to air after the release of the Ghostbusters II (1989) film. As a result, there are a number reference to the film. These include the appearance of Louis Tully and Janine Melnitz's new look (her appearance is modeled after Janine in the film). It is strongly implied that events of this episode take place around the time of the film. One difference between this episode and the film, however, is that the Ghostbusters never went out of business in the animated series; Janine refers to Peter and the Ghostbusters busting thousands of ghosts over many years and up to the present.
First episode in which Louis Tully wears a Ghostbusters uniform and operates a proton pack.
First episode to feature the new, Slimer-heavy montage during the closing credits.
The Big Greaser is a parody of the Bob's Big Boy restaurant chain.