This episode includes two reoccurring actors from the show "Bones." Joel David Moore and Carla Gallo play two of the squinterns on "Bones." Carla Gallo is also Dr. Sweets's girlfriend. Also, Erich Anderson guest-starred on "Bones" that same year.
At 28:50, House is watching a wrestling match featuring Christian Cage (Jay Reso) versus Abyss (Christopher Parks) for the NWA World Heavyweight Championship from TNA (now Impact) Wrestling's 2006 pay-per-view event, Lockdown.
Bailee Madison (Lucy) and Jennifer Morrison (Dr. Cameron) both star in ABC's Once Upon A Time, Madison as the younger version of Morrison's mother.