Based on the manga "Jin" by Motoka Murakami (published by by-weekly manga magazine Super Jump from 2000-2010).
Several of the characters in the fictional story were pivotal in reforming Japan during the Meiji Restoration.
Minakata Jin is often referred to as practicing Dutch medicine. Also known as rangaku, was a different practice to Japanese medicine of the era. Rangaku was learnt via a Dutch trading post notable for being the single place of direct trade and exchange between Japan and the outside world during the Edo period.