The apartment that House and Foreman visit in the "three days earlier" flashback scene has the same furniture as the apartment in Pulp Fiction (1994) where Jules and Vincent meet Marvin.
When House says, "And it would've worked too if it weren't for those meddling kids," he's quoting the Scooby Doo, Where Are You! (1969) cartoons when the villain at the end is unmasked.
House refers to the CEO of the advertisement company as "Don," a reference to Jon Hamm's character in Mad Men (2007).
Actress Haley Pullos (Colleen, the young girl House is talking to) played a recurring character on General Hospital (1963), established to be one of House's favorite TV shows.
House's ID pays homage to another famous detective, criminal rather than medical, as his address is 221 Baker Street, Apartment B. Sherlock Holmes' address is famously 221B Baker Street.