Angel's Friends is based on a series of Italian comics created by Simona Ferri and published by Play Press from March 2007 to January 2008.
In the comics, the Challenge Room, as it is known in cartoon, is called Recreational Class
In the comics, the average age of the characters being lower, Arkhan and Temptel don't teach "Positive Earthly Life" and "Negative Earthly Life" but "Positive Earthly Childhood" and "Negative Earthly Childhood".
The Angel, Dolce, the Devil, Misha, and the Neutral, Reina, don't appear in the comics, while the Angel, Ang-Lì, the Devil, Mefisto, and Raoul, the human of whom Raf is in love with, are not shown in the cartoon.
In the comics, Angels and Devils are forbidden to remove the shield that hides themselves and to interact with the humans: they must instead, advice them by using chibi projections of themselves, invisible, produced by the mascots. In the cartoon, instead, Angels and Devils transform into humans and advice their protected by talking to them or showing them the better behavior (or wrong) to be taken.