The wolf in this episode is the same wolf that Emma swerved to miss when she was trying to leave Storybrooke in Pilot (2011).
The wolf that played Graham's brother is also one of the wolves used to "design" the werewolves in the Twilight (2008) series.
The wolf, can be seen as a version of Snow White (skin as white as snow, lips as red of blood, hair black as night). The wolf fur is the skin. One eye shows the lips of Snow White, and the other shows the hair.
Originally, there were plans for a future story about Snow White using the whistle that the Huntsman made for her. The show creators "had something fun planned for that," but it never came to pass.
Jennifer Morrison pulled a muscle while shooting the fight scene with Regina, due to shooting the fight from so many different angles in the cold.