Shaggy said "There's an old saying in Crystal Cove: Fool me once, shame on...shame on you...a fooled man can't get fooled again". This is a near verbatim parody of what President George W. Bush said in 2002.
First episode of Hot Dog Water in the opening credits, displacing Daphne.
Baylor Hotner, star of the Dusk films, is a parody of Taylor Lautner, star of the Twilight movies. The real Lautner voiced guest characters in A Terrifying Round with a Menacing Metallic Clown (2005) and Camp Comeoniwannascareya (2005).
Matt Lanter, voice of Baylor Hotner, played Edward Sullen in Vampires Suck (2010), another Twilight Saga parody.