Blythe finally makes it to the Pet Expo. Unfortunately, the Biskit Twins sabotage her at every turn, making her think her nightmares about everything going wrong at the International Pet Fashion Expo might actually be coming true.
Blythe gets viral video star Felina Meow to appear at Littlest Pet Street's Grand Opening, but she and the pets have to fly to her island home to pick her up.
Blythe and friends try to help Sue overcome her reluctance to accept an award in front of the whole school while the pets delight in a sweet-smelling skunk day camper much to Pepper's dismay.
Blythe lives in the big city, right above the Littlest Pet Shop, a day-camp for all types of pets. When she discovers she can talk to the animals, it's the beginning of music-filled, zany adventures with her new four-legged friends.
Word gets out to the Downtown City pet population that Blythe can understand them and one morning the pet shop is besieged by those seeking her advice, including one little ferret that has Blythe doubting her abilities.
The pets try to help a painfully shy peacock get ready for his big debut at the botanical gardens while Youngmee tries to convince Blythe to use her ability to communicate with pets for the betterment of humanity.