HipHopDX reported that the song was renamed three times.
The song features Justin Timberlake and Timbaland, but most sources don't credit Timbaland for being on the song.
In 2008, it was nominated for a Grammy for Best Rap Song.
David Jeffries from AllMusic highlighted and wrote: "At ease is the Timbaland production "Ayo Technology" featuring Justin Timberlake, an obvious single that's "been there, done that" for all parties involved. This doesn't mean it's bland, just safe."
In September 2009, British singer Skyla released a cover version of the song.