Opens with the quote, "Oh, remember that you fashioned me from clay! Will you then bring me down to dust?" This is based on bible verse Job 10:9.
The episode title is most likely a play on the title of the song "Livin' on a Prayer" by Bon Jovi.
Guest star Don Alder appeared on a previous episode of Grimm (2011), Season 1, Episode 14: Plumed Serpent (2012), as Fred Eberhart.
Brigid Brannagh who plays Sara Fisher and Alexis Denisof (Viktor Albert Wilhelm George Beckendorf) portrayed a couple for awhile on the show "Angel". She was a guest star as Virginia Bryce, while he had a leading role as Wesley Wyndam-Pryce.