Sort by Popularity - Most Popular Movies and TV Shows tagged with keyword "experiment-gone-wrong"
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1. Once Upon a Time (2011–2018)
TV-PG | 60 min | Adventure, Fantasy, Romance
A young woman with a troubled past is drawn to a small town in Maine where fairy tales are to be believed.
Stars: Ginnifer Goodwin, Jennifer Morrison, Lana Parrilla, Robert Carlyle
Votes: 237,447
2. Jurassic Park (1993)
PG-13 | 127 min | Action, Adventure, Sci-Fi
A pragmatic paleontologist touring an almost complete theme park on an island in Central America is tasked with protecting a couple of kids after a power failure causes the park's cloned dinosaurs to run loose.
Director: Steven Spielberg | Stars: Sam Neill, Laura Dern, Jeff Goldblum, Richard Attenborough
Votes: 1,069,993 | Gross: $402.45M
3. Jurassic World Dominion (2022)
PG-13 | 147 min | Action, Adventure, Sci-Fi
Four years after the destruction of Isla Nublar, Biosyn operatives attempt to track down Maisie Lockwood, while Dr Ellie Sattler investigates a genetically engineered swarm of giant insects.
Director: Colin Trevorrow | Stars: Chris Pratt, Bryce Dallas Howard, Laura Dern, Sam Neill
Votes: 206,658 | Gross: $376.85M
4. Eternal Sunshine of the Spotless Mind (2004)
R | 108 min | Drama, Romance, Sci-Fi
When their relationship turns sour, a couple undergoes a medical procedure to have each other erased from their memories forever.
Director: Michel Gondry | Stars: Jim Carrey, Kate Winslet, Tom Wilkinson, Gerry Robert Byrne
Votes: 1,080,487 | Gross: $34.40M
5. Spider-Man (2002)
PG-13 | 121 min | Action, Adventure, Sci-Fi
After being bitten by a genetically-modified spider, a shy teenager gains spider-like abilities that he uses to fight injustice as a masked superhero and face a vengeful enemy.
Director: Sam Raimi | Stars: Tobey Maguire, Kirsten Dunst, Willem Dafoe, James Franco
Votes: 882,192 | Gross: $403.71M
6. Logan (2017)
R | 137 min | Action, Drama, Sci-Fi
In a future where mutants are nearly extinct, an elderly and weary Logan leads a quiet life. But when Laura, a mutant child pursued by scientists, comes to him for help, he must get her to safety.
Director: James Mangold | Stars: Hugh Jackman, Patrick Stewart, Dafne Keen, Boyd Holbrook
Votes: 833,987 | Gross: $226.28M
7. The Guest (I) (2014)
R | 100 min | Action, Mystery, Thriller
A soldier introduces himself to the Peterson family, claiming to be a friend of their son who died in action. After the young man is welcomed into their home, a series of accidental deaths seem to be connected to his presence.
Director: Adam Wingard | Stars: Dan Stevens, Sheila Kelley, Maika Monroe, Joel David Moore
Votes: 107,274 | Gross: $0.32M
8. Weird Science (1985)
PG-13 | 94 min | Comedy, Romance, Sci-Fi
Two high-school nerds use a computer program to literally create the perfect woman, who promptly turns their lives upside-down.
Director: John Hughes | Stars: Anthony Michael Hall, Ilan Mitchell-Smith, Kelly LeBrock, Bill Paxton
Votes: 97,680 | Gross: $23.83M
9. Jurassic World (2015)
PG-13 | 124 min | Action, Adventure, Sci-Fi
A new theme park, built on the original site of Jurassic Park, creates a genetically modified hybrid dinosaur, the Indominus Rex, which escapes containment and goes on a killing spree.
Director: Colin Trevorrow | Stars: Chris Pratt, Bryce Dallas Howard, Ty Simpkins, Judy Greer
Votes: 680,848 | Gross: $652.27M
10. The Mist (2007)
R | 126 min | Horror, Sci-Fi, Thriller
A freak storm unleashes a species of bloodthirsty creatures on a small town, where a small band of citizens hole up in a supermarket and fight for their lives.
Director: Frank Darabont | Stars: Thomas Jane, Marcia Gay Harden, Laurie Holden, Andre Braugher
Votes: 341,439 | Gross: $25.59M
11. Iron Man Three (2013)
PG-13 | 130 min | Action, Adventure, Sci-Fi
When Tony Stark's world is torn apart by a formidable terrorist called the Mandarin, he starts an odyssey of rebuilding and retribution.
Director: Shane Black | Stars: Robert Downey Jr., Guy Pearce, Gwyneth Paltrow, Don Cheadle
Votes: 901,058 | Gross: $409.01M
12. Fantastic Four (2015)
PG-13 | 100 min | Action, Adventure, Sci-Fi
Four young outsiders teleport to an alternate and dangerous universe which alters their physical form in shocking ways. The four must learn to harness their new abilities and work together to save Earth from a former friend turned enemy.
Director: Josh Trank | Stars: Miles Teller, Kate Mara, Michael B. Jordan, Jamie Bell
Votes: 176,862 | Gross: $56.12M
13. Venom (2018)
PG-13 | 112 min | Action, Adventure, Sci-Fi
A failed reporter is bonded to an alien entity, one of many symbiotes who have invaded Earth. But the being takes a liking to Earth and decides to protect it.
Director: Ruben Fleischer | Stars: Tom Hardy, Michelle Williams, Riz Ahmed, Scott Haze
Votes: 539,800 | Gross: $213.52M
14. The Incredible Hulk (2008)
PG-13 | 112 min | Action, Adventure, Sci-Fi
Bruce Banner, a scientist on the run from the U.S. Government, must find a cure for the monster he turns into whenever he loses his temper.
Director: Louis Leterrier | Stars: Edward Norton, Liv Tyler, Tim Roth, William Hurt
Votes: 524,466 | Gross: $134.52M
15. Species (1995)
R | 108 min | Action, Horror, Sci-Fi
A group of scientists try to track down and trap a killer alien seductress before she successfully mates with a human.
Director: Roger Donaldson | Stars: Natasha Henstridge, Michael Madsen, Ben Kingsley, Alfred Molina
Votes: 85,432 | Gross: $60.07M
16. Quantum Leap (1989–1993)
TV-PG | 60 min | Action, Adventure, Drama
During an experiment into time travel, a scientist finds himself trapped in the past, "leaping" into the lives of different people, sorting out their problems and changing history in hopes of getting back to his own life in the present.
Stars: Scott Bakula, Dean Stockwell, Deborah Pratt, Dennis Wolfberg
Votes: 36,566
17. Snowpiercer (2013)
R | 126 min | Action, Drama, Sci-Fi
In a future where a failed climate change experiment has killed all life except for the survivors who boarded the Snowpiercer (a train that travels around the globe), a new class system emerges.
Director: Bong Joon Ho | Stars: Chris Evans, Jamie Bell, Tilda Swinton, Ed Harris
Votes: 389,862 | Gross: $4.56M
18. Back to the Future Part II (1989)
PG | 108 min | Adventure, Comedy, Sci-Fi
After visiting 2015, Marty McFly must repeat his visit to 1955 to prevent disastrous changes to 1985...without interfering with his first trip.
Director: Robert Zemeckis | Stars: Michael J. Fox, Christopher Lloyd, Lea Thompson, Tom Wilson
Votes: 573,961 | Gross: $118.50M
19. Splice (2009)
R | 104 min | Horror, Sci-Fi
Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use.
Director: Vincenzo Natali | Stars: Adrien Brody, Sarah Polley, Delphine Chanéac, Brandon McGibbon
Votes: 101,905 | Gross: $17.00M
20. Captain Marvel (2019)
PG-13 | 123 min | Action, Adventure, Sci-Fi
Carol Danvers becomes one of the universe's most powerful heroes when Earth is caught in the middle of a galactic war between two alien races.
Directors: Anna Boden, Ryan Fleck | Stars: Brie Larson, Samuel L. Jackson, Ben Mendelsohn, Jude Law
Votes: 612,291 | Gross: $426.83M
21. Ad Astra (2019)
PG-13 | 123 min | Adventure, Drama, Mystery
Astronaut Roy McBride undertakes a mission across an unforgiving solar system to uncover the truth about his missing father and his doomed expedition that now, 30 years later, threatens the universe.
Director: James Gray | Stars: Brad Pitt, Tommy Lee Jones, Ruth Negga, Donald Sutherland
Votes: 261,038 | Gross: $50.19M
22. Hulk (2003)
PG-13 | 138 min | Action, Sci-Fi
Bruce Banner, a genetics researcher with a tragic past, suffers an accident that causes him to transform into a raging green monster when he gets angry.
Director: Ang Lee | Stars: Eric Bana, Jennifer Connelly, Sam Elliott, Josh Lucas
Votes: 278,960 | Gross: $132.18M
23. Resident Evil: Welcome to Raccoon City (2021)
R | 107 min | Action, Horror, Sci-Fi
Set in 1998, this origin story explores the secrets of the mysterious Spencer Mansion and the ill-fated Raccoon City.
Director: Johannes Roberts | Stars: Kaya Scodelario, Robbie Amell, Hannah John-Kamen, Tom Hopper
Votes: 64,420 | Gross: $17.00M
24. The Stand (1994)
Not Rated | 90 min | Adventure, Drama, Fantasy
After a deadly plague kills most of the world's population, the remaining survivors split into two groups - one led by a benevolent elder and the other by a malevolent being - to face each other in a final battle between good and evil.
Stars: Gary Sinise, Molly Ringwald, Jamey Sheridan, Laura San Giacomo
Votes: 38,496
25. Morbius (2022)
PG-13 | 104 min | Action, Adventure, Horror
Biochemist Michael Morbius tries to cure himself of a rare blood disease, but he inadvertently infects himself with a form of vampirism instead.
Director: Daniel Espinosa | Stars: Jared Leto, Matt Smith, Adria Arjona, Jared Harris
Votes: 154,012 | Gross: $73.87M
26. Dark Angel (2000–2002)
TV-14 | 60 min | Action, Drama, Mystery
A group of genetically-enhanced children escape from a lab project. Years later we meet Max, one of the escapees who now works for a messenger service in the post-apocalyptic Pacific Northwest.
Stars: Jessica Alba, Michael Weatherly, Richard Gunn, J.C. MacKenzie
Votes: 34,653
27. Push (2009)
PG-13 | 111 min | Action, Sci-Fi, Thriller
Two young Americans with special abilities must race to find a girl in Hong Kong before a shadowy government organization called Division does.
Director: Paul McGuigan | Stars: Camilla Belle, Dakota Fanning, Chris Evans, Colin Ford
Votes: 115,693 | Gross: $31.81M
28. Deep Blue Sea (1999)
R | 105 min | Action, Adventure, Sci-Fi
Searching for a cure to Alzheimer's disease, a group of scientists on an isolated research facility become the prey, as a trio of intelligent sharks fight back.
Director: Renny Harlin | Stars: Thomas Jane, Saffron Burrows, Samuel L. Jackson, Jacqueline McKenzie
Votes: 142,781 | Gross: $73.65M
29. Ghost in the Shell (2017)
PG-13 | 107 min | Action, Crime, Drama
In the near future, Major Mira Killian is the first of her kind: A human saved from a terrible crash, who is cyber-enhanced to be a perfect soldier devoted to stopping the world's most dangerous criminals.
Director: Rupert Sanders | Stars: Scarlett Johansson, Pilou Asbæk, Takeshi Kitano, Juliette Binoche
Votes: 228,263 | Gross: $40.56M
30. House on Haunted Hill (1999)
R | 93 min | Horror, Mystery, Thriller
An amusement park mogul offers a group of diverse people $1,000,000 to spend the night in a haunted house with a horrifying past.
Director: William Malone | Stars: Geoffrey Rush, Famke Janssen, Taye Diggs, Peter Gallagher
Votes: 60,234 | Gross: $40.85M
31. Monsters vs. Aliens (2009)
PG | 94 min | Animation, Action, Adventure
A woman transformed into a giant after she is struck by a meteorite on her wedding day becomes part of a team of monsters sent in by the U.S. government to defeat an alien mastermind trying to take over Earth.
Directors: Rob Letterman, Conrad Vernon | Stars: Reese Witherspoon, Rainn Wilson, Stephen Colbert, Seth Rogen
Votes: 176,491 | Gross: $198.35M
32. Piranha (1978)
R | 94 min | Comedy, Horror, Sci-Fi
When flesh-eating piranhas are accidentally released into a summer resort's rivers, the guests become their next meal.
Director: Joe Dante | Stars: Bradford Dillman, Heather Menzies-Urich, Kevin McCarthy, Keenan Wynn
Votes: 24,821 | Gross: $6.00M
33. The Nutty Professor (1996)
PG-13 | 95 min | Comedy, Romance, Sci-Fi
Grossly overweight yet good-hearted professor Sherman Klump takes a special chemical that turns him into the slim but obnoxious Buddy Love.
Director: Tom Shadyac | Stars: Eddie Murphy, Jada Pinkett Smith, James Coburn, Larry Miller
Votes: 123,926 | Gross: $128.81M
34. The Blob (1988)
R | 95 min | Horror, Sci-Fi, Thriller
A deadly entity from space crash-lands near a small town and begins consuming everyone in its path. Panic ensues as shady government scientists try to contain the horrific creature.
Director: Chuck Russell | Stars: Shawnee Smith, Kevin Dillon, Donovan Leitch Jr., Jeffrey DeMunn
Votes: 43,670 | Gross: $8.25M
35. Boss Level (2020)
TV-MA | 100 min | Action, Adventure, Comedy
Trapped in a time loop that constantly repeats the day of his murder, a former special forces agent must unlock the mystery behind his untimely demise.
Director: Joe Carnahan | Stars: Frank Grillo, Mel Gibson, Naomi Watts, Michelle Yeoh
Votes: 79,490
36. The Incredible Hulk (1978–1982)
TV-PG | 60 min | Action, Adventure, Drama
A fugitive scientist has the curse of becoming a powerful green monster under extreme emotional stress.
Stars: Bill Bixby, Lou Ferrigno, Jack Colvin, Charles Napier
Votes: 16,190
37. Sliders (1995–2000)
TV-PG | 60 min | Adventure, Fantasy, Sci-Fi
A boy genius and his comrades travel to different parallel universes, trying to find their way back home.
Stars: Jerry O'Connell, Sabrina Lloyd, John Rhys-Davies, Cleavant Derricks
Votes: 20,438
38. The Fantastic Four (1994)
PG | 90 min | Action, Adventure, Family
When dosed with cosmic rays, four intrepid explorers are given incredible powers.
Director: Oley Sassone | Stars: Alex Hyde-White, Jay Underwood, Rebecca Staab, Michael Bailey Smith
Votes: 7,589
39. Ant-Man and the Wasp (2018)
PG-13 | 118 min | Action, Adventure, Comedy
As Scott Lang balances being both a superhero and a father, Hope van Dyne and Dr. Hank Pym present an urgent new mission that finds the Ant-Man fighting alongside The Wasp to uncover secrets from their past.
Director: Peyton Reed | Stars: Paul Rudd, Evangeline Lilly, Michael Peña, Walton Goggins
Votes: 451,079 | Gross: $216.65M
40. Lights Out (II) (2016)
PG-13 | 81 min | Horror, Mystery
Rebecca must unlock the terror behind her little brother's experiences that once tested her sanity, bringing her face to face with a supernatural spirit attached to their mother.
Director: David F. Sandberg | Stars: Teresa Palmer, Gabriel Bateman, Maria Bello, Billy Burke
Votes: 142,678 | Gross: $67.27M
41. Hardcore Henry (2015)
R | 96 min | Action, Adventure, Sci-Fi
Henry is resurrected from death with no memory, and he must save his wife from a telekinetic warlord with a plan to bio-engineer soldiers.
Director: Ilya Naishuller | Stars: Sharlto Copley, Tim Roth, Haley Bennett, Danila Kozlovskiy
Votes: 102,088 | Gross: $9.25M
42. Humanoids from the Deep (1980)
R | 80 min | Horror, Sci-Fi
Humanoid sea creatures start killing a fishing town's residents, and raping their women. It's up to the townsfolk and a visiting biologist to fight back and fend them off.
Directors: Barbara Peeters, Jimmy T. Murakami | Stars: Doug McClure, Ann Turkel, Vic Morrow, Cindy Weintraub
Votes: 10,565
43. Firestarter (1984)
R | 114 min | Action, Horror, Sci-Fi
A couple who participated in a potent medical experiment gain telepathic ability and then have a child who is pyrokinetic.
Director: Mark L. Lester | Stars: Drew Barrymore, David Keith, Freddie Jones, Heather Locklear
Votes: 37,002 | Gross: $15.10M
44. Primer (2004)
PG-13 | 77 min | Drama, Sci-Fi, Thriller
Four friends/fledgling entrepreneurs, knowing that there's something bigger and more innovative than the different error-checking devices they've built, wrestle over their new invention.
Director: Shane Carruth | Stars: Shane Carruth, David Sullivan, Casey Gooden, Anand Upadhyaya
Votes: 114,378 | Gross: $0.42M
45. Leviathan (1989)
R | 98 min | Adventure, Horror, Mystery
Perched on the hull of a wrecked Soviet freighter, a team of deep-sea miners led by head oceanographer Steven Beck comes face to face with a mutant creature that's the product of a failed genetic experiment.
Director: George P. Cosmatos | Stars: Peter Weller, Richard Crenna, Amanda Pays, Daniel Stern
Votes: 23,887 | Gross: $15.70M
46. The Cloverfield Paradox (2018)
PG-13 | 102 min | Action, Horror, Sci-Fi
Orbiting a planet on the brink of war, scientists test a device to solve an energy crisis, and end up face-to-face with a dark alternate reality.
Director: Julius Onah | Stars: Gugu Mbatha-Raw, David Oyelowo, Daniel Brühl, John Ortiz
Votes: 113,243
47. Flubber (1997)
PG | 93 min | Comedy, Family, Sci-Fi
An absent-minded professor discovers "flubber," a rubber-like super-bouncy substance.
Director: Les Mayfield | Stars: Robin Williams, Marcia Gay Harden, Christopher McDonald, Ted Levine
Votes: 94,799 | Gross: $92.98M
48. Southland Tales (2006)
R | 145 min | Comedy, Drama, Mystery
During a three-day heat wave just before a huge 4th of July celebration, an action star stricken with amnesia meets up with a porn star who is developing her own reality TV project, and a policeman who holds the key to a vast conspiracy.
Director: Richard Kelly | Stars: Dwayne Johnson, Sarah Michelle Gellar, Seann William Scott, Carlos Amezcua
Votes: 40,691 | Gross: $0.28M
49. The Lawnmower Man (1992)
R | 108 min | Horror, Sci-Fi
A simple man is turned into a genius through the application of computer science.
Director: Brett Leonard | Stars: Jeff Fahey, Pierce Brosnan, Jenny Wright, Mark Bringelson
Votes: 39,118 | Gross: $32.10M
50. Flatliners (1990)
R | 115 min | Drama, Horror, Sci-Fi
Five medical students experiment with "near death" experiences, until the dark consequences of past tragedies begin to jeopardize their lives.
Director: Joel Schumacher | Stars: Kiefer Sutherland, Kevin Bacon, Julia Roberts, William Baldwin
Votes: 93,629 | Gross: $61.49M