Some of the voice cast who worked on this latest incarnation of the Littlest Pet Shop also worked on the previous 1995 cartoon incarnation as well.
Ashleigh Ball does Rainbow Dash's voice when she voices Blythe.
Blythe Baxter is one of (if not the only) animated character to have different clothes in every episode.
In Plane It on Rio! (2014), a scene from My Little Pony: Equestria Girls (2013) can be seen in which Twilight Sparkle is talking to Fluttershy.
Heidi is the only character to have the same name as her actress.